Posts by: Jose Marques Lopes, PhD

News

Hemophilia patients may now benefit from financial assistance for out-of-pocket expenses, health insurance premiums, and incidental medical costs following the launch of a new program from The Assistance Fund (TAF). ... Read more

June 25, 2018June 25, 2018

Oxidation of FVIII Increases Immune Response in Hemophilia A Mouse Model, Study Finds

News

Oxidation of clotting protein factor VIII (FVIII) increased the immune response to the replacement therapy in a mouse model of severe hemophilia A, a study found. Conducted by researchers ... Read more

June 22, 2018June 22, 2018

Developing Inhibitors Inflates Treatment Costs and Impairs Quality of Life, Study Finds

News

Hemophilia patients who develop inhibitors against treatment face markedly higher healthcare costs — about three times those of other patients — and experience poorer quality of life, according to a ... Read more

May 30, 2018May 30, 2018

BIVV001 Extends Lifetime of Hemophilia A Replacement Therapy, Early Trial Data Shows

News

Preliminary results of a Phase 1/2a trial of the hemophilia A experimental treatment BIVV001 show a significant extension of replacement therapy lifetime in the blood, Bioverativ announced. The ongoing, and ... Read more

May 20, 2018June 20, 2018

Joint Inflammation Can Lessen Life Quality in People with Severe Hemophilia, Study Says

News

Chronic joint inflammation lowers the health-related quality of life in people with severe hemophilia, a European study reports, and urges physicians to be aware of this association in treating ... Read more

April 9, 2018April 9, 2018

New Methods Can Help Identify Best Preventive Regimen for Children with Hemophilia A, Study Says

News

Researchers are creating a free web-based calculator that will help physicians determine the best patient-specific preventive regimens for children with hemophilia, according to a recent study. The tool is ... Read more

March 28, 2018March 28, 2018

Many Hemophilia B Patients Have Pain, Depression and Overall Poor Health, Study Finds

News

Many hemophilia B patients experience joint pain, depression and overall poor health, a study reports. Other findings were that women with hemophilia B had worse health than men and that those ... Read more

March 5, 2018

Sangamo Gets OK to Enroll UK Patients in Phase 1/2 Trial on SB-FIX, Potential Hemophilia B Therapy

News

A Phase 1/2 clinical trial on SB-FIX, an investigative gene-editing therapy for hemophilia B, is now authorized to enroll adult and adolescent patients in the U.K., Sangamo Therapeutics announced. Approval from the U.K.’s ... Read more

February 2, 2018February 2, 2018

Hemlibra Data Show Sustained Bleed Reductions in Hemophilia A Patients with Inhibitors

News

Clinical trials of Hemlibra (emicizumab-kxwh) continue to show significant reductions in bleeding episodes in patients with hemophilia A with inhibitors, Genentech recently announced. Data from Hemlibra’s clinical development program were ... Read more

January 24, 2018

Study Links Pro-Inflammatory Molecules and Immune Response to Hemophilia A Clotting Treatment

News

A major complication in scientists’ efforts to treat hemophilia A by replacing a missing or defective clotting factor is an immune response to the treatment. Researchers have discovered a ... Read more

Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

The Assistance Fund Offers New Program to Help Hemophilia Patients with Medical Expenses

Oxidation of FVIII Increases Immune Response in Hemophilia A Mouse Model, Study Finds

Developing Inhibitors Inflates Treatment Costs and Impairs Quality of Life, Study Finds

BIVV001 Extends Lifetime of Hemophilia A Replacement Therapy, Early Trial Data Shows

New Methods Can Help Identify Best Preventive Regimen for Children with Hemophilia A, Study Says

Many Hemophilia B Patients Have Pain, Depression and Overall Poor Health, Study Finds

Sangamo Gets OK to Enroll UK Patients in Phase 1/2 Trial on SB-FIX, Potential Hemophilia B Therapy

Hemlibra Data Show Sustained Bleed Reductions in Hemophilia A Patients with Inhibitors

Study Links Pro-Inflammatory Molecules and Immune Response to Hemophilia A Clotting Treatment

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