Sangamo Gets OK to Enroll UK Patients in Phase 1/2 Trial on SB-FIX, Potential Hemophilia B Therapy
A Phase 1/2 clinical trial on SB-FIX, an investigative gene-editing therapy for hemophilia B, is now authorized to enroll adult…
Articles by José Lopes, PhD
Hemlibra Data Show Sustained Bleed Reductions in Hemophilia A Patients with Inhibitors
Clinical trials of Hemlibra (emicizumab-kxwh) continue to show significant reductions in bleeding episodes in patients with hemophilia A with inhibitors,…
Study Links Pro-Inflammatory Molecules and Immune Response to Hemophilia A Clotting Treatment
A major complication in scientists’ efforts to treat hemophilia A by replacing a missing or defective clotting factor is an…
Hemophilia Puts Damper on Patients’ Sex Life and Health Status, Study Reports
Researchers report that hemophilia interferes with patients’ sexual activity and is linked to worse health status. The study titled “…
N8-GP Improves Quality of Life and Satisfaction of Children with Severe Hemophilia A, Study Finds
Researchers have found that N8-GP (turoctocog alfa pegol) treatment improved the quality of life and satisfaction of children with severe…
Catalyst Biosciences Starts Phase 2/3 Trial of Therapy to Prevent Hemophilia Bleeding Episodes
Catalyst Biosciences has begun enrolling patients in a Phase 2/3 clinical trial of marzeptacog alfa (activated) as a preventive treatment for…
Software to Help Personalize ADVATE Treatment of Hemophilia A Receives FDA Clearance
A web-based software to help personalize dosing regimens for some hemophilia A patients has received marketing clearance from the…
Certain B-Cells in Spleen Show Potential as Therapeutic Targets to Reduce FVIII Inhibitors in Hemophilia A, Study Shows
The spleen’s marginal zone (MZ) B-cells respond to blood coagulation factor VIII (FVIII) and show potential to become the target…
FDA Approves New, More Convenient Vial Strengths for Hemophilia A Therapy Nuwiq
The U.S. Food and Drug Administration has approved new vial strengths for Octopharma’s hemophilia A therapy Nuwiq, which means patients will…
uniQure Updates Gene Therapy Program in Treatment of Hemophilia B
Recent advances in gene therapy approaches to treat hemophilia B were recently announced by uniQure. The company achieved…