Xyntha (moroctocog alfa) for hemophilia
Xyntha (moroctocog alfa) is a recombinant, or man-made, clotting factor replacement therapy approved to prevent and treat bleeds, including those occurring during surgery, in people with hemophilia A.
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November 15, 2023
by Lindsey Shapiro, PhD
Afstyla (lonoctocog alfa) for hemophilia
Afstyla (lonoctocog alfa) is an injectable factor replacement therapy used to prevent and treat bleeding episodes, including those occurring during surgery, in people with hemophilia A.
November 9, 2023
by Marta Figueiredo, PhD
FEIBA (factor eight inhibitor bypassing activity) for hemophilia
FEIBA is an approved treatment for patients with hemophilia A and B, some of whom may have stopped responding to replacement therapy.
October 11, 2023
by Lindsey Shapiro, PhD
Idelvion (albutrepenonacog alfa) for hemophilia
Idelvion (albutrepenonacog alfa) is an approved factor IX (FIX) replacement therapy for the prevention and treatment of bleeds, including those occurring during surgery, in adults and children with hemophilia B.
April 10, 2023
by Lindsey Shapiro, PhD
Ixinity (trenonacog alfa) for hemophilia
Ixinity (trenonacog alfa; IB1001) is an approved replacement therapy designed to prevent or treat bleeding episodes in adults and children, ages 12 and older, with hemophilia B.
December 22, 2025
by Agata Boxe
Hemophilia and pregnancy: What to expect
Planning a pregnancy with hemophilia can bring up a lot of questions. While many pregnant women with the condition don’t experience major complications, careful planning and comprehensive care are needed to ensure the best outcomes for you and your baby. Learning about hemophilia and pregnancy, including…
Hympavzi boosts quality of life for hemophilia patients in trial
Hympavzi (marstacimab) reduced bleeding rates and improved quality of life in adults and adolescents with hemophilia A or B who have inhibitors (antibodies against standard replacement therapies). That’s according to final data from the Phase 3 BASIS study (NCT03938792), which demonstrated the treatment met its main goal of…
Liver rupture leads to hemophilia B diagnosis in newborn: Case report
A newborn in China was diagnosed with hemophilia B after a ruptured liver caused significant abdominal bleeding, according to a case report. Due to early detection, timely surgical repair, and immediate factor-replacement therapy, the infant made a full recovery. This case shows that “neonatal hepatic rupture may be…
December 10, 2025
by Agata Boxe
Understanding the difference between hemophilia A and B
While hemophilia A and hemophilia B are both bleeding disorders characterized by deficiencies in blood clotting factors, there are differences in one type versus the other, particularly in the specific genetic mutations that cause the disease, and in some of the treatment methods.