High Dose of Gene Therapy for Hemophilia B Normalizing FIX Levels, Early Trial Data Show
When administered at a high dose, a gene therapy for hemophilia B known as FLT180a seems able to restore the…
Articles by Marisa Wexler, MS
Esperoct Available in US to Treat Adults and Children with Hemophilia A, Novo Nordisk Says
Esperoct (turoctocog alfa pegol) is now available in the U.S. to treat and control bleeding in adults and children…
Modified Clotting Factor X Slowed Bleeding in Mouse Model of Hemophilia A, Study Reports
A modified version of the coagulation protein factor X was able to significantly reduce bleeding in a mouse model of…
Hemophilia Patients, Caregivers Identify Factors That Influence Decision to Switch Treatments
Ease of use, fear of the unknown, and healthcare providers’ advice are all major factors that play a role in…
Promising Interim Results Reported for uniQure’s Gene Therapy AMT-061 in Phase 2b Hemophilia B Trial
A single injection of uniQure‘s gene therapy AMT-061 (etranacogene dezaparvovec) is well-tolerated, effectively increases the levels of clotting…
Fitbit Can Be Used to Track Physical Activity in People with Hemophilia, Study Finds
The Fitbit wristband can help with the continuous monitoring of physical activity in people with hemophilia, but other…
Gene Therapy AMT-061 Provides Greater Factor IX Activity to Possibly Prevent Joint Disease, Study Reports
The gene therapies AMT-060 and AMT-061 both restored coagulation factor IX levels in a primate model of hemophilia B, but…
NovoSeven Linked to Low Rate of Dangerous Blood Clots in Review Study
Problematic thrombotic events are fairly rare in people using NovoSeven, among all types of bleeding disorders for which it is…
New Data Support Long-term Effectiveness of Preventive EHL Treatment in Hemophilia A and B
New data from clinical studies suggests that long-term preventive treatment of severe hemophilia A with Eloctate, or severe hemophilia…
Esperoct Approved in Canada for Treatment of Hemophilia A
Health Canada has approved Esperoct, an engineered formulation of clotting factor VIII, for the treatment of hemophilia…