Hemophilia is a rare blood disorder that primarily affects males, but females can be carriers of the disease. There are two different types of hemophilia carriers: possible carriers and obligate carriers.
According to Steps For Living, the mutated genes associated with hemophilia lie on the X chromosome. If a woman inherits a copy of an X chromosome with a defective XIII gene or IX gene, she may become a carrier of the disease and pass hemophilia onto her sons. Any daughters she has may also become carriers.
A woman is considered an obligate carrier if:
- Her father has hemophilia.
- She has one son with the disease and another close family member with hemophilia, such as a brother, grandfather, uncle, nephew, or first male cousin.
- She is the mother of more than one son with hemophilia.
A woman is considered a possible carrier if:
- Her mother is a carrier.
- She has one son who has hemophilia but no other close family members who are affected by the disease.
- She is a close family member of another carrier, such as a sister, aunt, grandmother, niece, or first female cousin.
Women can be tested to see if they are carriers in two ways. The first is through factor assays, which determine the amount of clotting factor in a woman’s blood. Unfortunately, this is not always accurate as carriers may have perfectly normal levels of clotting factor.
A more reliable way to discover if a woman is a hemophilia carrier is to undergo a genetic test to see if she has either of the mutated genes associated with the disease.
MORE: What causes hemophilia?
Hemophilia News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
We are sorry that this post was not useful for you!
Let us improve this post!
Tell us how we can improve this post?