Hemophilia is a rare disorder where a person’s blood lacks a factor which enables it to clot, leading to excessive bleeding that can become life-threatening. This bleeding can occur internally or externally. According to the World Federation of Hemophilia and the National Heart, Lung…
Hemophilia is classified as mild, moderate, or severe, depending on the level of clotting factor in the blood. About 70% of those with hemophilia have the severe form. The most important life-threatening complications of the disease are bleeding in the skull and hemorrhages in soft tissue around airways or other…
Novo Nordisk expects a decision this month by the U.S. Food and Drug Administration (FDA) on its product N9-GP  (nonacog beta pegol) as a treatment for hemophilia B. Approval of the drug may depend on the conclusions the FDA makes regarding safety concerns raised by its blood products advisory committee,…
The severity levels of hemophilia are determined by the level of residual/remaining clotting factor (factor VIII or factor IX) activity in the patient’s blood, which is denoted by the percentage of factor activity in the blood (or international units per ml of blood – IU/ml). According to the World Federation of Hemophilia,…
Taking charge of your health when you have hemophilia is of great importance. Regardless of your hemophilia type — A, B or C — the goal is to keep your joints strong and healthy, and to keep extra weight off to avoid muscle strains and bleeding in vulnerable joints. Obesity…
https://www.youtube.com/watch?v=NYdlke9Qo6w In this video from Medic Tube, find out how hemophilia patients can prevent joint bleeding. MORE: Researchers review guidelines on primary prophylaxis in hemophiliac children. The video explains that people often think the main issue for those who suffer from hemophilia is…
About hemophilia Hemophilia is an inherited X-linked recessive bleeding disorder, caused by a deficiency in coagulation factor VIII (hemophilia A), factor IX (hemophilia B), or factor XI (hemophilia C), that results from mutations in the clotting factor genes; it mainly affects males (hemophilia A and B, the two most common forms of…
UniQure‘s investigational gene therapy AMT-060 for severe hemophilia B has received PRIME designation by the European Medicines Agency (EMA). The EMA designation was based on the results of a Phase 1/2 open-label, dose-escalating study of AMT-060 (NCT02396342). The study included 10 patients, each receiving…
https://www.youtube.com/watch?v=0_EmvUb171I This video from Medic Tube gives an overview of the genetic causes behind hemophilia. The narrator explains that it’s very rare for females to have hemophilia because they need to inherit the faulty X gene from both of their parents, whereas males only need to inherit one…
Although hemophilia has no cure, there are ways to manage the disease and avoid bleeding episodes. We’ve put together a list of tips to help patients live well with hemophilia using information from the Mayo Clinic and the Centers for Disease Control and Prevention. MORE: World’s…
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